Crinone 8%: Vaginal Progesterone Quality and Consistency You Can Count On
![]() |
“[I]ssues of quality assurance regarding the purity, potency, and
quality of compounded products are a concern.”
— ACOG Committee on Gynecologic Practice, 20052
Study confirms quality concerns with pharmacy-compounded vaginal progesterone1
A recent study compared the quality of extemporaneously compounded progesterone vaginal suppositories received from 10 randomly selected compounding pharmacies across the United States.
- 80% of pharmacies tested failed potency tests
References: 1. Mahugana V, McDermott JM, Zhang F, Ochoa F. Investigation of product quality between extemporaneously compounded progesterone vaginal suppositories and an approved progesterone vaginal gel. Drug Dev Indust Pharm. 2004;30;1069–1078. 2. ACOG Committee on Gynecologic Practice. Committee opinion no. 322: Compounded bioidentical hormones. Obstet Gynecol. 2005;106:1139–1140.





