The Comfort of Powerful Progesterone Support   Progesterone deficiency can make it more difficult for women to become pregnant or to maintain pregnancy.   Crinone 8% provides safe and effective progesterone support for women who have a progesterone deficiency and who are undergoing infertility treatment.

Crinone 8% comes in the form of a vaginal gel that is easy to apply once a day. In several clinical studies, women undergoing infertility treatment consistently preferred Crinone 8% over progesterone intramuscular injections, progesterone vaginal suppositories, and progesterone capsules administered vaginally.

Learn more about Crinone 8%

Crinone 8% (progesterone gel) is indicated for progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesterone deficiency.

Important Safety Information

The most common side effects of CRINONE (progesterone gel) 8% include breast enlargement, constipation, drowsiness, nausea, headache, and pain in the pubic area. You should not use CRINONE 8% if you have any disorders involving blockage of your blood vessels, or a history of these disorders, miscarriages, vaginal bleeding that hasn’t been diagnosed, liver problems or disease, or known or possible cancer of the breast or genital organs. You should discontinue use of CRINONE 8% if any symptoms occur that signal a blockage of your blood vessels. There is no adequate evidence that CRINONE 8% will work in preventing miscarriage. Your doctor should examine your breasts and pelvic organs, as well as perform a Pap smear prior to prescribing CRINONE 8%. If you have vaginal bleeding during treatment with CRINONE 8%, your doctor should look for the cause. If you have conditions that cause fluid retention, a history or depression, or diabetes, your doctor should provide special attention to your care while you are using CRINONE 8%.