Helping Dreams
of Pregnancy Come True.

• Prescribing Information
• Patient Information
• Glossary
• Share

• 
• The Menstrual Cycle
• Role of Progesterone in Pregnancy
• About CRINONE
  • CRINONE for
    Progesterone Support
  • Patient Preference
  • Features of CRINONE
  • How to Use CRINONE
• FAQs
• Resources

Indication and Usage

CRINONE 8% (progesterone gel) is indicated for progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesterone deficiency.

Important Safety Information

The most common side effects of CRINONE 8% (progesterone gel) include breast enlargement, constipation, drowsiness, nausea, headache, and pain in the pubic area. You should not use CRINONE 8% if you have any disorders involving blockage of your blood vessels, or a history of these disorders, miscarriages, vaginal bleeding that hasn’t been diagnosed, liver problems or disease, or known or possible cancer of the breast or genital organs. You should discontinue use of CRINONE 8% if any symptoms occur that signal a blockage of your blood vessels. There is no evidence that CRINONE 8% will work in preventing miscarriage. Your doctor should examine your breasts and pelvic organs, as well as perform a Pap smear prior to prescribing CRINONE 8%. If you have vaginal bleeding during treatment with CRINONE 8%, your doctor should look for the cause. If you have conditions that cause fluid retention, a history of depression, or diabetes, your doctor should provide special attention to your care while you are using CRINONE 8%.

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